D-Chiro Inositol
D-Chiro Inositol
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D-Chiro Inositol & D-Pinnitol16 comments to D-Chiro Inositol & D-Pinnitol |
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I am currently obtaining my Masters in Dietetics and Nutrtion and have been trying to compound enough data on the benefits of inositol for PCOS.
I am trying to put together a study and intervention for PCOS patients that will focus on dietary changes as well as natural supplementation focusing on the inositol family.
Any information would be very helpful as I would love to help in my quest to make life and pregnancy much easier for us all.
Thank you for all your research!
Ashley,
Thank you for your kind comments – it really makes spending all the time and effort researching this and putting this website together worthwhile, to know that there are people out there whom it is helping.
The reference section at the bottom of pages or, if I have been especially longwinded as in the DCI article – the Links to Resources page: http://pcosinfo.wordpress.com/treatments/natural/dci/resources/ is a good place to start … when you have a solid week to read it all
I will email you with copies of some of the relevant studies that I have saved.
Do let me know how you go, and if there’s anything I can do to assist with the study. I studied Orthomolecular Nutrition and did a post graduate Diploma in Clinical Nutrition about a million years ago myself … it’s a very interesting field.
Kind regards,
Anne
Hi, how can I order some of this DCI from you?
Hi Sam,
It’s easy, all I need is an email telling me:
* Your full name
* The address you want the DCI posted to
* How many grams of DCI you would like (it doesn’t have to be a multiple of the 18 g packets, I can measure out a custom quantity based on your needs)
* Whether you would like the DCI sent via regular mail, express post or registered mail.
I will then send you a quote/invoice and payment details and if you are happy with it, once you have paid for it, I will ship it that same day. I can accept payment via Paypal (though there is a small extra charge to cover their fees), or direct deposit into my Australian bank account or by telegraphic transfer from an overseas bank account.
Too easy!
I look forward to hearing from you again.
Kind regards,
Anne
What is the recommended dosage with the DCI powder? I was told that if your weight is under 130lbs/60kilos, you should take 600mg in capsule form and if you are over, to take 1200mg. Is the dosage different with the powder?
As DCI is still the subject of clinical trials, it is a little too early to say what ‘the recommended dosage’ is. The information you have been given has likely been tailored by a company that sells DCI in 600 mg increments. As with most drugs and supplements, the right dosage for each individual will vary based on a number of factors such as age, weight, the amount of carbohydrates consumed and the type (low or high GI).
The earlier studies ten years ago were based on a dose of 1200 mg DCI once daily in the morning for overweight women and 600 mg once daily in the morning for lean women, and this is likely where the advice you received about the capsules came from. The more recent studies and clinical results have been trialling amounts up to 3000 mg per day and in divided doses rather than once daily.
Therefore, the current recommendation, whether for powder or capsules as they are essentially identical, is to take between 10 and 20 mg per kilogram of your bodyweight per day in two or three separate doses. This is much easier to achieve with the powder as you can measure out precisely how much you should be having at each time, rather than having to ‘make do’ with 600 mg capsules.
For instance if you weigh 132 lb or 60 kg, you could take between 600 and 1200 mg per day. If you weigh 220 lbs or 100 kg your recommended daily therapeutic dose would be between 1000 mg and 2000 mg.
Lindsey,
I will write back to you personally and attach some studies for you, but essentially I personally feel it is better to have the pure DCI powder without all the fillers etc as they can have a negative effect on digestion, causing nausea in some cysters. The active ingredient is identical – in fact I believe it is manufactured by the same chemist.
Kind regards,
Anne
Dear Anne,
Thanks so much for such a swift reply! You’ve answered a lot of my questions
effectively with just one simple email.
I would be interested in seeing any of the studies you might have at your
disposal, if it is not too much of an inconvenience. I guess my last
question would be your opinion of the quality of the powder versus the
capsules. I was looking into Chiral Balance capsules, but recently found
some information about ‘filler’ put in the capsules that dilutes the actual
DCI.
Thanks again,
Lindsey
I believe the chiralbalance has 0 fillers and is using a mushroom gelatin based capsule that is proven not to interfere.
I need know how can I Order D-Chiro and how much is , I am at Kansas USA – Thank you!
Hi Vivi,
DCI is $30 AUD for 18 grams, $150 for 100 grams ($25 per 18 grams) or $280 for 200 grams ($21.60 per 18 grams). This equates to between $1.40 and $1.67 per gram and is the cheapest DCI being retailed in the world at present, to the best of my knowledge.
Postage rates to the USA for 18 or 36 grams by regular airmail is $2.40 AUD. 100 grams costs $4.60 by regular Airmail and 200 grams costs $7.10. Registered Mail costs $20 AUD for up to 500 gm.
If you send me an email to anne@mypcos.info with the amount you wish to order and the type of postage you require (regular Airmail or registered) I will send you a Paypal invoice which you can pay from either a bank account or credit card without the need to sign up for a Paypal account.
I look forward to hearing from you.
Kind regards, Anne
Hi, a few questions.
1. Where is it manufactured?
2. What are the company’s details – name, are they registered etc?
3. What is it manufactured from?
4. Where do you import it from?
5. Does the manufacturer provide a guarantee that is is DCI and pharmaceutical grade? Can you make this available to your customers?
6. What benefits have you found from taking it and how long had you being taking it before you found it helpful?
7. What other treatments do you take and why?
Thanks for taking the time to reply.
Hello
Tonight I went to a new doctor who recommended I visit your website to read about dci for a pcos problem I’ve have for 15 years. I’m at the stage in life where I want to try and fall pregnant. I haven’t had a period in years…. the doctor prescribed me progesterone which I will start taking tomorrow…and I was thinking ill combine it with dci. I have a few questions though….
1.Can I take the two together?
2. Is science safe to take once pregnant?
3. What dosage are u required to take… how long will 18 grams last
And 4. How is it consumed???
Sorry for all the questions, this is all very new to me!!
Thanks for your help.
Melissa
Dear Melissa,
Thank you for your email regarding DCI. I’m very glad to hear that
your doctor referred you to my website and I’m happy to answer any questions that you or they might have.
Let me answer your questions in the format in which you asked them:
1. Yes it is safe to take progesterone and DCI together, in fact I do
so occasionally myself. DCI’s primary mechanism of action revolves
around insulin signal transduction and through it carbohydrate
metabolism. If you take DCI, you may not require progesterone after a
few months, but this is something for you and your doctor to monitor
together. Progesterone levels are low in women with PCOS ultimately
because of hyperinsulinaemia. Once this is addressed, through
increasing insulin sensitivity or DCI supplementation, progesterone
levels should increase again. I’ve attached some studies which found
this to be the case. You may find them interesting, or you may wish
to take them to your Dr for them to read.
2. This is a difficult question to answer categorically. It’s a very
personal choice. All I can do is tell you what I know and what I
would do if I were pregnant. There have not been, nor are there ever
likely to be, studies done on the safety of DCI during pregnancy. As
it is not patentable, being identical to a substance manufactured in
nature, there is insufficient monetary incentive for anyone to fund
these studies. On the other hand, I can tell you that:
DCI is a substance found in healthy human bodies, which plays a
critical role in carbohydrate metabolism through the insulin
signalling pathway.
We take supplemental DCI because women with PCOS/IR etc appear to have
a defect in inositol metabolism which prevents us from obtaining DCI
from food, manufacturing it from inositol in vivo and also makes us
excrete whatever DCI we do manage to obtain many times more quickly
than other human beings. In summary, we are restoring the status quo,
rather than taking a nutrient in doses larger than normally obtained
through the diet in order to achieve a pseudo-pharmaceutical effect.
DCI is naturally derived, close to 100% pure chemically and is
something that can be found in some foods.
By regulating carbohydrate metabolism and normalising elevated insulin
and blood glucose levels, DCI helps to balance female reproductive
hormones, by preventing the inhibition of progesterone production
which occurs with elevated levels of testosterone (a side effect of
elevated insulin levels). Progesterone is essential for sustaining
pregnancy. It is the ‘pregnancy hormone’. If there is insufficient
progesterone, miscarriage is likely. Progesterone insufficiency is
the leading cause of miscarriage amongst women with PCOS. The
placenta will takeover progesterone production from around the 12th
week, which is when the risk of miscarriage is greatly reduced.
During pregnancy, insulin sensitivity is dulled in everyone, not just
those with PCOS/IR. All women are at higher risk of diabetes during
pregnancy or in later life partially as a result of pregnancy.
Gestational diabetes is usually transitory, resolving after birth,
however, it increases the risk of diabetes in later life for both the
mother and the child. Elevated insulin and blood sugar levels during
pregnancy have a negative effect on the foetus.
I cannot advise you on the right course of action – this is a decision
that ultimately only you can make, in conjunction with your doctor.
All I can do is share with you what I would do. If I were pregnant I
would definitely continue taking my DCI. I consider it likely to be
an exceptionally safe substance. I believe that the risks of not
taking it vastly outweigh any potential risks of taking it.
3. Clinical results indicate that an initial dosing regimen of at
least 20 mg per kg of bodyweight is required to effect results. For a
60kg (132lb) woman this would be 1200mg per day. On this dose, 18g
will last for 15 days. For a 90kg woman (198lbs) this would be 1800mg
per day. On this dose 18 g will last for 10 days.
4. I sell DCI as a powder with a little custom measuring scoop which
measures out 100mg of DCI. It’s easier to take an appropriate dose
for your bodyweight this way and the DCI tastes very much like sugar.
Given that we have to be incredibly strict with everything else sweet,
it seems like a wasted opportunity to hide something so delicious away
in a capsule and it also saves on packaging and postage, making it
cheaper for you as well.
On a personal note, I had not had a period for 3.5 years when I first
discovered DCI. I had one four weeks after I started taking 1200mg a
day (at the time I required more than this, but was not aware of the 20mg/kg recommendation) and my cycle has become progressively more
regular since then. I hope it will work for you as well.
If you or your doctor have any further questions, please let me know.
I’m here to help.
Kind regards,
Anne
Hi Anne, thanks for the info and support. I just wanted to give you a quick update on how I’ve been going since starting DCI three months ago. I wish I could tell you that I’m pregnant but unfortunately that hasn’t happened yet. But I know that the DCI is helping me. I noticed a difference in my acne in the first week. Now after three months my skin is almost perfectly clear. I cannot remember the last time it looked this good! I have been having regular cycles and blood tests in the last two months have confirmed that I have ovulated in those cycles. I’ve also noticed a positive effect on my moods. They seem more stable. I hope one day soon I can report back that DCI has helped me get pregnant. But in the meantime I know it is helping to balance my hormones and is helping me to look healthier and feel better about me. Thanks again for distributing DCI in Australia. I only wish I discovered it earlier. Take care, B
Thanks Brooke! I’m glad to hear that you are noticing so much improvement. Good luck for next month! Anne